Anastrozole (Oral, Tablets)

What it may help with

What's included

• Evaluation and prescription by a licensed clinician, when appropriate.
• Compounded Anastrozole, prepared by a state-licensed pharmacy.
• 2-day, discreet monthly shipping.
• Ongoing access to a board-certified clinical team for questions and dose adjustments.
• The ability to pause, delay, or cancel your subscription at any time.

Why patients choose this

• A small tablet rather than another injection
• Targeted support specifically for elevated estradiol on TRT
• Dose-flexible based on individual conversion patterns and lab work
• An option for men who have tried TRT alone and need additional hormone support

Your timeline

1. TodayPlace your order and complete medical intake form.
2. Days 1-2Clinical team reviews in 1-2 business days, and when appropriate, prescribes.
3. Days 3-5Pharmacy prepares your order.
4. Days 5-7Your order ships directly to you with 2-day shipping.
5. Every 4 weeksYour order renews. Payment is processed and the product shipped to you.

What to expect

1. Getting startedTake it by mouth as directed by your clinician, often a low dose a couple of times per week.
2. Weeks 1–2If your estrogen was elevated, symptoms like water retention or breast tenderness may begin to ease as levels come down.
3. OngoingDosing is fine-tuned to keep estrogen balanced as part of your broader hormone plan. The goal is the right level, not the lowest.

Lab work requirement

Lab work is not required. However, Anastrozole is generally prescribed as part of a testosterone therapy plan, which requires lab testing. For information on testosterone therapy, you may refer to the testosterone therapy product page.

Possible side effects

Important information

A note on dosing philosophy

Estrogen isn't a "male" or "female" hormone; men need a healthy amount of it for bone health, mood, libido, and cardiovascular function. The goal of anastrozole in TRT is to manage estrogen that's running too high, not to eliminate it. Aggressive estrogen suppression often causes more problems than it solves: joint pain, low libido, mood changes, and bone loss over time. Your clinician will dose conservatively and use lab work to keep estradiol in a healthy range for men.

• Anastrozole is a prescription medication, prescribed off-label for hormone management in men on testosterone therapy. The FDA-approved version of anastrozole (Arimidex) is for the treatment of hormone receptor-positive breast cancer in postmenopausal women; its use in men is off-label, based on a growing body of clinical experience.

• This medication is compounded, meaning it's custom-prepared by a state-licensed pharmacy at the specific low dose your clinician prescribes.

• Anastrozole is generally prescribed alongside testosterone therapy, not on its own. Your clinician will determine whether it fits your hormone plan based on your labs and symptoms.

• Possible side effects include joint pain or stiffness, mood changes, fatigue, and over time, effects on bone density if estradiol is suppressed too aggressively. Your clinician will monitor for these.

• Not everyone is a candidate. Your clinician will review your medical history, possible side effects, and whether this treatment is right for you.

• Results vary and are not guaranteed.